CRK FISH Probe
The CRK FISH probe is designed to hybridize to the CRK gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CRK-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CRK-20-RE | 20 (40 μL) | 200 μL |  |
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| CRK-20-GO | 20 (40 μL) | 200 μL |  |
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| CRK-20-GR | 20 (40 μL) | 200 μL |  |
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| CRK-20-AQ | 20 (40 μL) | 200 μL |  |
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| CRK-20-DIG | 20 (40 μL) | 200 μL |  |
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| CRK-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CRK
Gene Name: CRK Proto-oncogene, Adaptor Protein
Chromosome: CHR17: 1325457-1359544
Locus: 17p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CRK FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CRK-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping