CRH1 FISH Probe
The CRH1 FISH probe is designed to hybridize to the CRH1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CRH-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CRH-20-RE | 20 (40 μL) | 200 μL |  |
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| CRH-20-GO | 20 (40 μL) | 200 μL |  |
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| CRH-20-GR | 20 (40 μL) | 200 μL |  |
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| CRH-20-AQ | 20 (40 μL) | 200 μL |  |
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| CRH-20-DIG | 20 (40 μL) | 200 μL |  |
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| CRH-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the corticotropin-releasing factor family. The encoded preproprotein is proteolytically processed to generate the mature neuropeptide hormone. In response to stress, this hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus, binds to corticotropin releasing hormone receptors and stimulates the release of adrenocorticotropic hormone from the pituitary gland. Marked reduction in this protein has been observed in association with Alzheimer's disease. Autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes, and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition. [provided by RefSeq, Nov 2015]
Gene Details
Gene Symbol: CRH
Gene Name: Corticotropin Releasing Hormone
Chromosome: CHR8: 67088611-67090846
Locus: 8q13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CRH1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CRH-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping