CRFG FISH Probe
The CRFG FISH probe is designed to hybridize to the CRFG gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
GTPBP4-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
GTPBP4-20-RE | 20 (40 μL) | 200 μL | ||
GTPBP4-20-GO | 20 (40 μL) | 200 μL | ||
GTPBP4-20-GR | 20 (40 μL) | 200 μL | ||
GTPBP4-20-AQ | 20 (40 μL) | 200 μL | ||
GTPBP4-20-DIG | 20 (40 μL) | 200 μL | ||
GTPBP4-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: GTPBP4
Gene Name: GTP Binding Protein 4
Chromosome: CHR10: 1034348-1063708
Locus: 10p15.3
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CRFG FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GTPBP4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping