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CREBBP FISH Probe

The CREBBP FISH probe is designed to hybridize to the CREBBP gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

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Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CREBBP-20-OR  (Standard Design) 20 (40 μL) 200 μL
CREBBP-20-RE 20 (40 μL) 200 μL
CREBBP-20-GO 20 (40 μL) 200 μL
CREBBP-20-GR 20 (40 μL) 200 μL
CREBBP-20-AQ 20 (40 μL) 200 μL
CREBBP-20-DIG 20 (40 μL) 200 μL
CREBBP-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009]

Gene Details

Gene Symbol: CREBBP

Gene Name: CREB Binding Protein

Chromosome: CHR16: 3775055-3930121

Locus: 16p13.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: CREBBP FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: CREBBP-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping