COX7A2L FISH Probe
The COX7A2L FISH probe is designed to hybridize to the COX7A2L gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| COX7A2L-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| COX7A2L-20-RE | 20 (40 μL) | 200 μL |  |
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| COX7A2L-20-GO | 20 (40 μL) | 200 μL |  |
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| COX7A2L-20-GR | 20 (40 μL) | 200 μL |  |
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| COX7A2L-20-AQ | 20 (40 μL) | 200 μL |  |
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| COX7A2L-20-DIG | 20 (40 μL) | 200 μL |  |
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| COX7A2L-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene. [provided by RefSeq, Jan 2016]
Gene Details
Gene Symbol: COX7A2L
Gene Name: Cytochrome C Oxidase Subunit 7A2 Like
Chromosome: CHR2: 42577644-42588356
Locus: 2p21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: COX7A2L FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: COX7A2L-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping