COX6A1 FISH Probe
The COX6A1 FISH probe is designed to hybridize to the COX6A1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| COX6A1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| COX6A1-20-RE | 20 (40 μL) | 200 μL |  |
|
| COX6A1-20-GO | 20 (40 μL) | 200 μL |  |
|
| COX6A1-20-GR | 20 (40 μL) | 200 μL |  |
|
| COX6A1-20-AQ | 20 (40 μL) | 200 μL |  |
|
| COX6A1-20-DIG | 20 (40 μL) | 200 μL |  |
|
| COX6A1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (liver isoform) of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66% amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1, 6, 7q21, 7q31-32 and 12. However, only one pseudogene (COX6A1P) on chromosome 1p31.1 has been documented. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: COX6A1
Gene Name: Cytochrome C Oxidase Subunit 6A1
Chromosome: CHR12: 120875903-120878529
Locus: 12q24.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: COX6A1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: COX6A1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping