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COX11 FISH Probe

The COX11 FISH probe is designed to hybridize to the COX11 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
COX11-20-OR  (Standard Design) 20 (40 μL) 200 μL
COX11-20-RE 20 (40 μL) 200 μL
COX11-20-GO 20 (40 μL) 200 μL
COX11-20-GR 20 (40 μL) 200 μL
COX11-20-AQ 20 (40 μL) 200 μL
COX11-20-DIG 20 (40 μL) 200 μL
COX11-20-BIO 20 (40 μL) 200 μL

Gene Summary

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6. [provided by RefSeq, Jun 2009]

Gene Details

Gene Symbol: COX11

Gene Name: COX11, Cytochrome C Oxidase Copper Chaperone

Chromosome: CHR17: 53029258-53046064

Locus: 17q22

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: COX11 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: COX11-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping