COX11 FISH Probe
The COX11 FISH probe is designed to hybridize to the COX11 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| COX11-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| COX11-20-RE | 20 (40 μL) | 200 μL |  |
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| COX11-20-GO | 20 (40 μL) | 200 μL |  |
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| COX11-20-GR | 20 (40 μL) | 200 μL |  |
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| COX11-20-AQ | 20 (40 μL) | 200 μL |  |
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| COX11-20-DIG | 20 (40 μL) | 200 μL |  |
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| COX11-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6. [provided by RefSeq, Jun 2009]
Gene Details
Gene Symbol: COX11
Gene Name: COX11, Cytochrome C Oxidase Copper Chaperone
Chromosome: CHR17: 53029258-53046064
Locus: 17q22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: COX11 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: COX11-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping