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COX10 FISH Probe

The COX10 FISH probe is designed to hybridize to the COX10 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

SKU Test Kits Buffer Dye Color Order Now
COX10-20-OR  (Standard Design) 20 (40 μL) 200 μL
COX10-20-RE 20 (40 μL) 200 μL
COX10-20-GO 20 (40 μL) 200 μL
COX10-20-GR 20 (40 μL) 200 μL
COX10-20-AQ 20 (40 μL) 200 μL
COX10-20-DIG 20 (40 μL) 200 μL
COX10-20-BIO 20 (40 μL) 200 μL

Gene Summary

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: COX10

Gene Name: COX10, Heme A:farnesyltransferase Cytochrome C Oxidase Assembly Factor

Chromosome: CHR17: 13972718-14111996

Locus: 17p12

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: COX10 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: COX10-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping