COX IV-1 FISH Probe
The COX IV-1 FISH probe is designed to hybridize to the COX IV-1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| COX4I1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| COX4I1-20-RE | 20 (40 μL) | 200 μL |  |
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| COX4I1-20-GO | 20 (40 μL) | 200 μL |  |
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| COX4I1-20-GR | 20 (40 μL) | 200 μL |  |
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| COX4I1-20-AQ | 20 (40 μL) | 200 μL |  |
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| COX4I1-20-DIG | 20 (40 μL) | 200 μL |  |
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| COX4I1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
Gene Details
Gene Symbol: COX4I1
Gene Name: Cytochrome C Oxidase Subunit 4I1
Chromosome: CHR16: 85833172-85840607
Locus: 16q24.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: COX IV-1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: COX4I1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping