COM1 FISH Probe
The COM1 FISH probe is designed to hybridize to the COM1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RBBP8-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RBBP8-20-RE | 20 (40 μL) | 200 μL |  |
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| RBBP8-20-GO | 20 (40 μL) | 200 μL |  |
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| RBBP8-20-GR | 20 (40 μL) | 200 μL |  |
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| RBBP8-20-AQ | 20 (40 μL) | 200 μL |  |
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| RBBP8-20-DIG | 20 (40 μL) | 200 μL |  |
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| RBBP8-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: RBBP8
Gene Name: RB Binding Protein 8, Endonuclease
Chromosome: CHR18: 20513294-20606449
Locus: 18q11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: COM1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RBBP8-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping