COL25A1 Break Apart FISH Probe
Empire Genomics’ COL25A1 Break Apart FISH Probe is designed to flank the COL25A1 gene and is typically used for detecting COL25A1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| COL25A1BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| COL25A1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| COL25A1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| COL25A1BA-20-GORE | 20 (40 μL) | 200 μL |
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| COL25A1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| COL25A1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| COL25A1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| COL25A1BA-20-REGO | 20 (40 μL) | 200 μL |
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| COL25A1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over-expression of this collagen in mice, however, found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Details
Gene Symbol: COL25A1
Gene Name: Collagen Type XXV Alpha 1 Chain
Chromosome: CHR4: 109734971-110223799
Locus: 4q25
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: COL25A1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: COL25A1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping