COL1A2 Break Apart FISH Probe
Empire Genomics’ COL1A2 Break Apart FISH Probe is designed to flank the COL1A2 gene and is typically used for detecting COL1A2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| COL1A2BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| COL1A2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| COL1A2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| COL1A2BA-20-GORE | 20 (40 μL) | 200 μL |
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| COL1A2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| COL1A2BA-20-GROR | 20 (40 μL) | 200 μL |
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| COL1A2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| COL1A2BA-20-REGO | 20 (40 μL) | 200 μL |
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| COL1A2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
Gene Details
Gene Symbol: COL1A2
Gene Name: Collagen Type I Alpha 2 Chain
Chromosome: CHR7: 94023872-94060544
Locus: 7q21.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: COL1A2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: COL1A2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping