COASY FISH Probe
The COASY FISH probe is designed to hybridize to the COASY gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| COASY-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| COASY-20-RE | 20 (40 μL) | 200 μL |  |
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| COASY-20-GO | 20 (40 μL) | 200 μL |  |
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| COASY-20-GR | 20 (40 μL) | 200 μL |  |
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| COASY-20-AQ | 20 (40 μL) | 200 μL |  |
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| COASY-20-DIG | 20 (40 μL) | 200 μL |  |
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| COASY-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Coenzyme A (CoA) functions as a carrier of acetyl and acyl groups in cells and thus plays an important role in numerous synthetic and degradative metabolic pathways in all organisms. In eukaryotes, CoA and its derivatives are also involved in membrane trafficking and signal transduction. This gene encodes the bifunctional protein coenzyme A synthase (CoAsy) which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5). The phosphopantetheine adenylyltransferase domain of this bifunctional protein catalyzes the conversion of 4'-phosphopantetheine into dephospho-coenzyme A (dpCoA) while its dephospho-CoA kinase domain completes the final step by phosphorylating dpCoA to form CoA. Mutations in this gene are associated with neurodegeneration with brain iron accumulation (NBIA). Alternative splicing results in multiple isoforms. [provided by RefSeq, Apr 2014]
Gene Details
Gene Symbol: COASY
Gene Name: Coenzyme A Synthase
Chromosome: CHR17: 40714091-40718295
Locus: 17q21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: COASY FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: COASY-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping