CO2 FISH Probe
The CO2 FISH probe is designed to hybridize to the CO2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| C2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| C2-20-RE | 20 (40 μL) | 200 μL |  |
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| C2-20-GO | 20 (40 μL) | 200 μL |  |
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| C2-20-GR | 20 (40 μL) | 200 μL |  |
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| C2-20-AQ | 20 (40 μL) | 200 μL |  |
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| C2-20-DIG | 20 (40 μL) | 200 μL |  |
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| C2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.[provided by RefSeq, Mar 2009]
Gene Details
Gene Symbol: C2
Gene Name: Complement C2
Chromosome: CHR6_dbb_hap3: 3154357-3199037
Locus: 6p21.33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CO2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: C2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping