CMS20 FISH Probe
The CMS20 FISH probe is designed to hybridize to the CMS20 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SLC5A7-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SLC5A7-20-RE | 20 (40 μL) | 200 μL |  |
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| SLC5A7-20-GO | 20 (40 μL) | 200 μL |  |
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| SLC5A7-20-GR | 20 (40 μL) | 200 μL |  |
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| SLC5A7-20-AQ | 20 (40 μL) | 200 μL |  |
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| SLC5A7-20-DIG | 20 (40 μL) | 200 μL |  |
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| SLC5A7-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from increased density of this protein in synaptosomal plasma membranes in response to depolarization of cholinergic terminals. Dysfunction of cholinergic signaling has been implicated in various disorders including depression, attention-deficit disorder, and schizophrenia. An allelic variant of this gene is associated with autosomal dominant distal hereditary motor neuronopathy type VIIA. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Gene Details
Gene Symbol: SLC5A7
Gene Name: Solute Carrier Family 5 Member 7
Chromosome: CHR2: 108602994-108630443
Locus: 2q12.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CMS20 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SLC5A7-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping