CMKRL2 FISH Probe
The CMKRL2 FISH probe is designed to hybridize to the CMKRL2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GPER1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| GPER1-20-RE | 20 (40 μL) | 200 μL |  |
|
| GPER1-20-GO | 20 (40 μL) | 200 μL |  |
|
| GPER1-20-GR | 20 (40 μL) | 200 μL |  |
|
| GPER1-20-AQ | 20 (40 μL) | 200 μL |  |
|
| GPER1-20-DIG | 20 (40 μL) | 200 μL |  |
|
| GPER1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum and a member of the G-protein coupled receptor 1 family. This receptor binds estrogen and activates multiple downstream signaling pathways, leading to stimulation of adenylate cyclase and an increase in cyclic AMP levels, while also promoting intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. This receptor has been shown to play a role in diverse biological processes, including bone and nervous system development, metabolism, cognition, male fertility and uterine function. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: GPER1
Gene Name: G Protein-coupled Estrogen Receptor 1
Chromosome: CHR7: 1086806-1093814
Locus: 7p22.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: CMKRL2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GPER1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping