CMKBR1 FISH Probe
The CMKBR1 FISH probe is designed to hybridize to the CMKBR1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CCR1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CCR1-20-RE | 20 (40 μL) | 200 μL |  |
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| CCR1-20-GO | 20 (40 μL) | 200 μL |  |
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| CCR1-20-GR | 20 (40 μL) | 200 μL |  |
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| CCR1-20-AQ | 20 (40 μL) | 200 μL |  |
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| CCR1-20-DIG | 20 (40 μL) | 200 μL |  |
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| CCR1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CCR1
Gene Name: C-C Motif Chemokine Receptor 1
Chromosome: CHR3: 46243199-46249832
Locus: 3p21.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CMKBR1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CCR1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping