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CMD1NN FISH Probe

The CMD1NN FISH probe is designed to hybridize to the CMD1NN gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
RAF1-20-OR  (Standard Design) 20 (40 μL) 200 μL
RAF1-20-RE 20 (40 μL) 200 μL
RAF1-20-GO 20 (40 μL) 200 μL
RAF1-20-GR 20 (40 μL) 200 μL
RAF1-20-AQ 20 (40 μL) 200 μL
RAF1-20-DIG 20 (40 μL) 200 μL
RAF1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: RAF1

Gene Name: Raf-1 Proto-oncogene, Serine/threonine Kinase

Chromosome: CHR3: 12625099-12705700

Locus: 3p25.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: CMD1NN FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: RAF1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping