CLOCK Break Apart FISH Probe
Empire Genomics’ CLOCK Break Apart FISH Probe is designed to flank the CLOCK gene and is typically used for detecting CLOCK rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CLOCKBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| CLOCKBA-20-AQOR | 20 (40 μL) | 200 μL |
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| CLOCKBA-20-GOGR | 20 (40 μL) | 200 μL |
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| CLOCKBA-20-GORE | 20 (40 μL) | 200 μL |
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| CLOCKBA-20-GRGO | 20 (40 μL) | 200 μL |
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| CLOCKBA-20-GRRE | 20 (40 μL) | 200 μL |
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| CLOCKBA-20-ORGR | 20 (40 μL) | 200 μL |
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| CLOCKBA-20-REGO | 20 (40 μL) | 200 μL |
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| CLOCKBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Polymorphisms in this gene may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Gene Details
Gene Symbol: CLOCK
Gene Name: Clock Circadian Regulator
Chromosome: CHR4: 56298659-56412997
Locus: 4q12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CLOCK FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CLOCK-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping