CLN13 FISH Probe
The CLN13 FISH probe is designed to hybridize to the CLN13 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CTSF-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CTSF-20-RE | 20 (40 μL) | 200 μL |  |
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| CTSF-20-GO | 20 (40 μL) | 200 μL |  |
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| CTSF-20-GR | 20 (40 μL) | 200 μL |  |
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| CTSF-20-AQ | 20 (40 μL) | 200 μL |  |
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| CTSF-20-DIG | 20 (40 μL) | 200 μL |  |
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| CTSF-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CTSF
Gene Name: Cathepsin F
Chromosome: CHR11: 66330934-66336047
Locus: 11q13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CLN13 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CTSF-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping