CLK2 Break Apart FISH Probe
Empire Genomics’ CLK2 Break Apart FISH Probe is designed to flank the CLK2 gene and is typically used for detecting CLK2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CLK2BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| CLK2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| CLK2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| CLK2BA-20-GORE | 20 (40 μL) | 200 μL |
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| CLK2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| CLK2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| CLK2BA-20-ORGR | 20 (40 μL) | 200 μL |
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| CLK2BA-20-REGO | 20 (40 μL) | 200 μL |
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| CLK2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Gene Details
Gene Symbol: CLK2
Gene Name: CDC Like Kinase 2
Chromosome: CHR1: 155232658-155243281
Locus: 1q22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CLK2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CLK2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping