CLDN8 FISH Probe
The CLDN8 FISH probe is designed to hybridize to the CLDN8 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CLDN8-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CLDN8-20-RE | 20 (40 μL) | 200 μL |  |
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| CLDN8-20-GO | 20 (40 μL) | 200 μL |  |
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| CLDN8-20-GR | 20 (40 μL) | 200 μL |  |
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| CLDN8-20-AQ | 20 (40 μL) | 200 μL |  |
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| CLDN8-20-DIG | 20 (40 μL) | 200 μL |  |
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| CLDN8-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.[provided by RefSeq, May 2010]
Gene Details
Gene Symbol: CLDN8
Gene Name: Claudin 8
Chromosome: CHR21: 31586323-31588469
Locus: 21q22.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CLDN8 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CLDN8-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping