CLDN14 FISH Probe
The CLDN14 FISH probe is designed to hybridize to the CLDN14 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CLDN14-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CLDN14-20-RE | 20 (40 μL) | 200 μL |  |
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| CLDN14-20-GO | 20 (40 μL) | 200 μL |  |
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| CLDN14-20-GR | 20 (40 μL) | 200 μL |  |
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| CLDN14-20-AQ | 20 (40 μL) | 200 μL |  |
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| CLDN14-20-DIG | 20 (40 μL) | 200 μL |  |
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| CLDN14-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2010]
Gene Details
Gene Symbol: CLDN14
Gene Name: Claudin 14
Chromosome: CHR21: 37832919-37948867
Locus: 21q22.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CLDN14 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CLDN14-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping