CLCN4 Break Apart FISH Probe
Empire Genomics’ CLCN4 Break Apart FISH Probe is designed to flank the CLCN4 gene and is typically used for detecting CLCN4 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CLCN4BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CLCN4BA-20-AQOR | 20 (40 μL) | 200 μL |
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| CLCN4BA-20-GOGR | 20 (40 μL) | 200 μL |
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| CLCN4BA-20-GORE | 20 (40 μL) | 200 μL |
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| CLCN4BA-20-GRGO | 20 (40 μL) | 200 μL |
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| CLCN4BA-20-GROR | 20 (40 μL) | 200 μL |
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| CLCN4BA-20-GRRE | 20 (40 μL) | 200 μL |
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| CLCN4BA-20-REGO | 20 (40 μL) | 200 μL |
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| CLCN4BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the voltage-gated chloride channel (ClC) family. The encoded protein is present in all cell types and localized in plasma membranes and in intracellular vesicles. It is a multi-pass membrane protein which contains a ClC domain and two additional C-terminal CBS (cystathionine beta-synthase) domains. The ClC domain catalyzes the selective flow of Cl- ions across cell membranes, and the CBS domain may have a regulatory function. This protein plays a role in both acidification and transmitter loading of GABAergic synaptic vesicles, and in smooth muscle cell activation and neointima formation. This protein is required for lysophosphatidic acid (LPA)-activated Cl- current activity and fibroblast-to-myofibroblast differentiation. The protein activity is regulated by Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) in glioma cells. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Gene Details
Gene Symbol: CLCN3
Gene Name: Chloride Voltage-gated Channel 3
Chromosome: CHR4: 170541671-170644338
Locus: 4q33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CLCN4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CLCN3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping