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CLAC FISH Probe

The CLAC FISH probe is designed to hybridize to the CLAC gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
COL25A1-20-OR  (Standard Design) 20 (40 μL) 200 μL
COL25A1-20-RE 20 (40 μL) 200 μL
COL25A1-20-GO 20 (40 μL) 200 μL
COL25A1-20-GR 20 (40 μL) 200 μL
COL25A1-20-AQ 20 (40 μL) 200 μL
COL25A1-20-DIG 20 (40 μL) 200 μL
COL25A1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over-expression of this collagen in mice, however, found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Gene Details

Gene Symbol: COL25A1

Gene Name: Collagen Type XXV Alpha 1 Chain

Chromosome: CHR4: 109734971-110223799

Locus: 4q25

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: CLAC FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: COL25A1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping