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CL1 FISH Probe

The CL1 FISH probe is designed to hybridize to the CL1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
DCLK1-20-OR  (Standard Design) 20 (40 μL) 200 μL
DCLK1-20-RE 20 (40 μL) 200 μL
DCLK1-20-GO 20 (40 μL) 200 μL
DCLK1-20-GR 20 (40 μL) 200 μL
DCLK1-20-AQ 20 (40 μL) 200 μL
DCLK1-20-DIG 20 (40 μL) 200 μL
DCLK1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported, but the full-length nature and biological validity of some variants have not been defined. These variants encode different isoforms, which are differentially expressed and have different kinase activities.[provided by RefSeq, Sep 2010]

Gene Details

Gene Symbol: DCLK1

Gene Name: Doublecortin Like Kinase 1

Chromosome: CHR13: 36342788-36705514

Locus: 13q13.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: CL1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: DCLK1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping