CKMT1B FISH Probe
The CKMT1B FISH probe is designed to hybridize to the CKMT1B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CKMT1B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CKMT1B-20-RE | 20 (40 μL) | 200 μL |  |
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| CKMT1B-20-GO | 20 (40 μL) | 200 μL |  |
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| CKMT1B-20-GR | 20 (40 μL) | 200 μL |  |
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| CKMT1B-20-AQ | 20 (40 μL) | 200 μL |  |
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| CKMT1B-20-DIG | 20 (40 μL) | 200 μL |  |
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| CKMT1B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CKMT1B
Gene Name: Creatine Kinase, Mitochondrial 1B
Chromosome: CHR15: 43885251-43891604
Locus: 15q15.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CKMT1B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CKMT1B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping