CIS-2 FISH Probe
The CIS-2 FISH probe is designed to hybridize to the CIS-2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SOCS2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SOCS2-20-RE | 20 (40 μL) | 200 μL |  |
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| SOCS2-20-GO | 20 (40 μL) | 200 μL |  |
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| SOCS2-20-GR | 20 (40 μL) | 200 μL |  |
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| SOCS2-20-AQ | 20 (40 μL) | 200 μL |  |
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| SOCS2-20-DIG | 20 (40 μL) | 200 μL |  |
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| SOCS2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has pseudogenes on chromosomes 20 and 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
Gene Details
Gene Symbol: SOCS2
Gene Name: Suppressor Of Cytokine Signaling 2
Chromosome: CHR12: 93963597-93969978
Locus: 12q22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CIS-2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SOCS2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping