CIS FISH Probe
The CIS FISH probe is designed to hybridize to the CIS gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CISH-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CISH-20-RE | 20 (40 μL) | 200 μL |  |
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| CISH-20-GO | 20 (40 μL) | 200 μL |  |
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| CISH-20-GR | 20 (40 μL) | 200 μL |  |
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| CISH-20-AQ | 20 (40 μL) | 200 μL |  |
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| CISH-20-DIG | 20 (40 μL) | 200 μL |  |
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| CISH-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Gene Details
Gene Symbol: CISH
Gene Name: Cytokine Inducible SH2 Containing Protein
Chromosome: CHR3: 50643884-50649262
Locus: 3p21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CIS FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CISH-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping