CII-SDHB FISH Probe
The CII-SDHB FISH probe is designed to hybridize to the CII-SDHB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SDHB-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SDHB-20-RE | 20 (40 μL) | 200 μL |  |
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| SDHB-20-GO | 20 (40 μL) | 200 μL |  |
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| SDHB-20-GR | 20 (40 μL) | 200 μL |  |
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| SDHB-20-AQ | 20 (40 μL) | 200 μL |  |
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| SDHB-20-DIG | 20 (40 μL) | 200 μL |  |
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| SDHB-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: SDHB
Gene Name: Succinate Dehydrogenase Complex Iron Sulfur Subunit B
Chromosome: CHR1: 17345224-17380665
Locus: 1p36.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CII-SDHB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SDHB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping