CII-4 FISH Probe
The CII-4 FISH probe is designed to hybridize to the CII-4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SDHD-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SDHD-20-RE | 20 (40 μL) | 200 μL |  |
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| SDHD-20-GO | 20 (40 μL) | 200 μL |  |
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| SDHD-20-GR | 20 (40 μL) | 200 μL |  |
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| SDHD-20-AQ | 20 (40 μL) | 200 μL |  |
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| SDHD-20-DIG | 20 (40 μL) | 200 μL |  |
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| SDHD-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]
Gene Details
Gene Symbol: SDHD
Gene Name: Succinate Dehydrogenase Complex Subunit D
Chromosome: CHR11: 111957570-111966518
Locus: 11q23.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CII-4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SDHD-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping