CHRNA4 Break Apart FISH Probe
Empire Genomics’ CHRNA4 Break Apart FISH Probe is designed to flank the CHRNA4 gene and is typically used for detecting CHRNA4 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CHRNA4BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| CHRNA4BA-20-AQOR | 20 (40 μL) | 200 μL |
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| CHRNA4BA-20-GOGR | 20 (40 μL) | 200 μL |
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| CHRNA4BA-20-GORE | 20 (40 μL) | 200 μL |
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| CHRNA4BA-20-GRGO | 20 (40 μL) | 200 μL |
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| CHRNA4BA-20-GRRE | 20 (40 μL) | 200 μL |
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| CHRNA4BA-20-ORGR | 20 (40 μL) | 200 μL |
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| CHRNA4BA-20-REGO | 20 (40 μL) | 200 μL |
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| CHRNA4BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
Gene Details
Gene Symbol: CHRNA4
Gene Name: Cholinergic Receptor Nicotinic Alpha 4 Subunit
Chromosome: CHR20: 61974664-61992695
Locus: 20q13.33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CHRNA4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CHRNA4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping