CHRNA4 FISH Probe
The CHRNA4 FISH probe is designed to hybridize to the CHRNA4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CHRNA4-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| CHRNA4-20-RE | 20 (40 μL) | 200 μL |  |
|
| CHRNA4-20-GO | 20 (40 μL) | 200 μL |  |
|
| CHRNA4-20-GR | 20 (40 μL) | 200 μL |  |
|
| CHRNA4-20-AQ | 20 (40 μL) | 200 μL |  |
|
| CHRNA4-20-DIG | 20 (40 μL) | 200 μL |  |
|
| CHRNA4-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
Gene Details
Gene Symbol: CHRNA4
Gene Name: Cholinergic Receptor Nicotinic Alpha 4 Subunit
Chromosome: CHR20: 61974664-61992695
Locus: 20q13.33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: CHRNA4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CHRNA4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping