CHML Break Apart FISH Probe
Empire Genomics’ CHML Break Apart FISH Probe is designed to flank the CHML gene and is typically used for detecting CHML rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CHMLBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| CHMLBA-20-AQOR | 20 (40 μL) | 200 μL |
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| CHMLBA-20-GOGR | 20 (40 μL) | 200 μL |
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| CHMLBA-20-GORE | 20 (40 μL) | 200 μL |
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| CHMLBA-20-GRGO | 20 (40 μL) | 200 μL |
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| CHMLBA-20-GRRE | 20 (40 μL) | 200 μL |
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| CHMLBA-20-ORGR | 20 (40 μL) | 200 μL |
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| CHMLBA-20-REGO | 20 (40 μL) | 200 μL |
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| CHMLBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia; also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]
Gene Details
Gene Symbol: CHM
Gene Name: CHM, Rab Escort Protein 1
Chromosome: CHRX: 85116184-85302566
Locus: Xq21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CHML FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CHM-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping