CHM-I FISH Probe
The CHM-I FISH probe is designed to hybridize to the CHM-I gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CNMD-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CNMD-20-RE | 20 (40 μL) | 200 μL |  |
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| CNMD-20-GO | 20 (40 μL) | 200 μL |  |
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| CNMD-20-GR | 20 (40 μL) | 200 μL |  |
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| CNMD-20-AQ | 20 (40 μL) | 200 μL |  |
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| CNMD-20-DIG | 20 (40 μL) | 200 μL |  |
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| CNMD-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CNMD
Gene Name: Chondromodulin
Chromosome: CHR13: 52739811-52703263
Locus: 13q14.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CHM-I FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CNMD-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping