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CHM FISH Probe

The CHM FISH probe is designed to hybridize to the CHM gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CHM-20-OR  (Standard Design) 20 (40 μL) 200 μL
CHM-20-RE 20 (40 μL) 200 μL
CHM-20-GO 20 (40 μL) 200 μL
CHM-20-GR 20 (40 μL) 200 μL
CHM-20-AQ 20 (40 μL) 200 μL
CHM-20-DIG 20 (40 μL) 200 μL
CHM-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia; also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]

Gene Details

Gene Symbol: CHM

Gene Name: CHM, Rab Escort Protein 1

Chromosome: CHRX: 85116184-85302566

Locus: Xq21.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: CHM FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: CHM-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping