CHIT FISH Probe
The CHIT FISH probe is designed to hybridize to the CHIT gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CHIT1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CHIT1-20-RE | 20 (40 μL) | 200 μL |  |
|
| CHIT1-20-GO | 20 (40 μL) | 200 μL |  |
|
| CHIT1-20-GR | 20 (40 μL) | 200 μL |  |
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| CHIT1-20-AQ | 20 (40 μL) | 200 μL |  |
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| CHIT1-20-DIG | 20 (40 μL) | 200 μL |  |
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| CHIT1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2012]
Gene Details
Gene Symbol: CHIT1
Gene Name: Chitinase 1
Chromosome: CHR1: 203185206-203198860
Locus: 1q32.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CHIT FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CHIT1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping