CGI-PDE FISH Probe
The CGI-PDE FISH probe is designed to hybridize to the CGI-PDE gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PDE3A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PDE3A-20-RE | 20 (40 μL) | 200 μL |  |
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| PDE3A-20-GO | 20 (40 μL) | 200 μL |  |
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| PDE3A-20-GR | 20 (40 μL) | 200 μL |  |
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| PDE3A-20-AQ | 20 (40 μL) | 200 μL |  |
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| PDE3A-20-DIG | 20 (40 μL) | 200 μL |  |
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| PDE3A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Gene Details
Gene Symbol: PDE3A
Gene Name: Phosphodiesterase 3A
Chromosome: CHR12: 20522196-20833881
Locus: 12p12.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CGI-PDE FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PDE3A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping