CGI-10 FISH Probe
The CGI-10 FISH probe is designed to hybridize to the CGI-10 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| COQ6-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| COQ6-20-RE | 20 (40 μL) | 200 μL |  |
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| COQ6-20-GO | 20 (40 μL) | 200 μL |  |
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| COQ6-20-GR | 20 (40 μL) | 200 μL |  |
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| COQ6-20-AQ | 20 (40 μL) | 200 μL |  |
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| COQ6-20-DIG | 20 (40 μL) | 200 μL |  |
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| COQ6-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the mitochondrial electron transport chain, and one of the most potent lipophilic antioxidants implicated in the protection of cell damage by reactive oxygen species. Knockdown of this gene in mouse and zebrafish results in decreased growth due to increased apoptosis. Mutations in this gene are associated with autosomal recessive coenzyme Q10 deficiency-6 (COQ10D6), which manifests as nephrotic syndrome with sensorineural deafness. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2012]
Gene Details
Gene Symbol: COQ6
Gene Name: Coenzyme Q6, Monooxygenase
Chromosome: CHR14: 74416636-74429813
Locus: 14q24.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CGI-10 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: COQ6-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping