CG5072-PB FISH Probe
The CG5072-PB FISH probe is designed to hybridize to the CG5072-PB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CDK4-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CDK4-20-RE | 20 (40 μL) | 200 μL |  |
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| CDK4-20-GO | 20 (40 μL) | 200 μL |  |
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| CDK4-20-GR | 20 (40 μL) | 200 μL |  |
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| CDK4-20-AQ | 20 (40 μL) | 200 μL |  |
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| CDK4-20-DIG | 20 (40 μL) | 200 μL |  |
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| CDK4-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CDK4
Gene Name: Cyclin Dependent Kinase 4
Chromosome: CHR12: 58141509-58146230
Locus: 12q14.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CG5072-PB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CDK4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping