CG42317-PL FISH Probe
The CG42317-PL FISH probe is designed to hybridize to the CG42317-PL gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CSK-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CSK-20-RE | 20 (40 μL) | 200 μL |  |
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| CSK-20-GO | 20 (40 μL) | 200 μL |  |
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| CSK-20-GR | 20 (40 μL) | 200 μL |  |
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| CSK-20-AQ | 20 (40 μL) | 200 μL |  |
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| CSK-20-DIG | 20 (40 μL) | 200 μL |  |
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| CSK-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is involved in multiple pathways, including the regulation of Src family kinases. It plays an important role in T-cell activation through its association with the protein encoded by the protein tyrosine phosphatase, non-receptor type 22 (PTPN22) gene. This protein also phosphorylates C-terminal tyrosine residues on multiple substrates, including the protein encoded by the SRC proto-oncogene, non-receptor tyrosine kinase gene. Phosphorylation suppresses the kinase activity of the Src family tyrosine kinases. An intronic polymorphism (rs34933034) in this gene has been found to affect B-cell activation and is associated with systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: CSK
Gene Name: C-terminal Src Kinase
Chromosome: CHR15: 75074424-75095539
Locus: 15q24.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CG42317-PL FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CSK-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping