CG3314-PD FISH Probe
The CG3314-PD FISH probe is designed to hybridize to the CG3314-PD gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RPL7A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RPL7A-20-RE | 20 (40 μL) | 200 μL |  |
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| RPL7A-20-GO | 20 (40 μL) | 200 μL |  |
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| RPL7A-20-GR | 20 (40 μL) | 200 μL |  |
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| RPL7A-20-AQ | 20 (40 μL) | 200 μL |  |
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| RPL7A-20-DIG | 20 (40 μL) | 200 μL |  |
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| RPL7A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L7AE family of ribosomal proteins. It can interact with a subclass of nuclear hormone receptors, including thyroid hormone receptor, and inhibit their ability to transactivate by preventing their binding to their DNA response elements. This gene is included in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. It is co-transcribed with the U24, U36a, U36b, and U36c small nucleolar RNA genes, which are located in its second, fifth, fourth, and sixth introns, respectively. This gene rearranges with the trk proto-oncogene to form the chimeric oncogene trk-2h, which encodes an oncoprotein consisting of the N terminus of ribosomal protein L7a fused to the receptor tyrosine kinase domain of trk. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: RPL7A
Gene Name: Ribosomal Protein L7a
Chromosome: CHR9: 136215068-136218280
Locus: 9q34.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CG3314-PD FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RPL7A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping