CFTR Break Apart FISH Probe
Empire Genomics’ CFTR Break Apart FISH Probe is designed to flank the CFTR gene and is typically used for detecting CFTR rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
CFTRBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
CFTRBA-20-AQOR | 20 (40 μL) | 200 μL | ||
CFTRBA-20-GOGR | 20 (40 μL) | 200 μL | ||
CFTRBA-20-GORE | 20 (40 μL) | 200 μL | ||
CFTRBA-20-GRGO | 20 (40 μL) | 200 μL | ||
CFTRBA-20-GROR | 20 (40 μL) | 200 μL | ||
CFTRBA-20-GRRE | 20 (40 μL) | 200 μL | ||
CFTRBA-20-REGO | 20 (40 μL) | 200 μL | ||
CFTRBA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. The encoded protein functions as a chloride channel, making it unique among members of this protein family, and controls ion and water secretion and absorption in epithelial tissues. Channel activation is mediated by cycles of regulatory domain phosphorylation, ATP-binding by the nucleotide-binding domains, and ATP hydrolysis. Mutations in this gene cause cystic fibrosis, the most common lethal genetic disorder in populations of Northern European descent. The most frequently occurring mutation in cystic fibrosis, DeltaF508, results in impaired folding and trafficking of the encoded protein. Multiple pseudogenes have been identified in the human genome. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: CFTR
Gene Name: Cystic Fibrosis Transmembrane Conductance Regulator
Chromosome: CHR7: 117120016-117308718
Locus: 7q31.2
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: CFTR FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CFTR-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping