CFL1 Break Apart FISH Probe
Empire Genomics’ CFL1 Break Apart FISH Probe is designed to flank the CFL1 gene and is typically used for detecting CFL1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CFL1BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| CFL1BA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| CFL1BA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| CFL1BA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| CFL1BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| CFL1BA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| CFL1BA-20-ORGR | 20 (40 μL) | 200 μL |
|
|
| CFL1BA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| CFL1BA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]
Gene Details
Gene Symbol: CFL1
Gene Name: Cofilin 1
Chromosome: CHR11: 65622284-65625804
Locus: 11q13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: CFL1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CFL1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping