CEP57 Break Apart FISH Probe
Empire Genomics’ CEP57 Break Apart FISH Probe is designed to flank the CEP57 gene and is typically used for detecting CEP57 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CEP57BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CEP57BA-20-AQOR | 20 (40 μL) | 200 μL |
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| CEP57BA-20-GOGR | 20 (40 μL) | 200 μL |
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| CEP57BA-20-GORE | 20 (40 μL) | 200 μL |
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| CEP57BA-20-GRGO | 20 (40 μL) | 200 μL |
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| CEP57BA-20-GROR | 20 (40 μL) | 200 μL |
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| CEP57BA-20-GRRE | 20 (40 μL) | 200 μL |
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| CEP57BA-20-REGO | 20 (40 μL) | 200 μL |
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| CEP57BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a cytoplasmic protein called Translokin. This protein localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of this protein is required for its centrosome localization and for its multimerization, and the C-terminal half is required for nucleating, bundling and anchoring microtubules to the centrosomes. This protein specifically interacts with fibroblast growth factor 2 (FGF2), sorting nexin 6, Ran-binding protein M and the kinesins KIF3A and KIF3B, and thus mediates the nuclear translocation and mitogenic activity of the FGF2. It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells. This protein is crucial for maintaining correct chromosomal number during cell division. Mutations in this gene cause mosaic variegated aneuploidy syndrome, a rare autosomal recessive disorder. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Gene Details
Gene Symbol: CEP57
Gene Name: Centrosomal Protein 57
Chromosome: CHR11: 95523624-95565857
Locus: 11q21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CEP57 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CEP57-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping