CENPS Break Apart FISH Probe
Empire Genomics’ CENPS Break Apart FISH Probe is designed to flank the CENPS gene and is typically used for detecting CENPS rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CENPSBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| CENPSBA-20-AQOR | 20 (40 μL) | 200 μL |
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| CENPSBA-20-GOGR | 20 (40 μL) | 200 μL |
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| CENPSBA-20-GORE | 20 (40 μL) | 200 μL |
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| CENPSBA-20-GRGO | 20 (40 μL) | 200 μL |
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| CENPSBA-20-GRRE | 20 (40 μL) | 200 μL |
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| CENPSBA-20-ORGR | 20 (40 μL) | 200 μL |
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| CENPSBA-20-REGO | 20 (40 μL) | 200 μL |
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| CENPSBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF(II)31, which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumors, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway. The protein is a component of multiple complexes, including the Fanconi anemia (FA) core complex, the APITD1/CENPS complex, and the CENPA-CAD (nucleosome distal) complex. Known functions include an involvement with chromatin associations of the FA core complex, and a role in the stable assembly of the outer kinetochore. Alternative splicing of this gene results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream cortistatin (CORT) gene, as represented in GeneID:100526739. An APITD1-related pseudogene has been identified on chromosome 7. [provided by RefSeq, Nov 2010]
Gene Details
Gene Symbol: CENPS
Gene Name: Centromere Protein S
Chromosome: CHR1: 10430101-10442814
Locus: 1p36.22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CENPS FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CENPS-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping