CENPL Break Apart FISH Probe
Empire Genomics’ CENPL Break Apart FISH Probe is designed to flank the CENPL gene and is typically used for detecting CENPL rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CENPLBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| CENPLBA-20-AQOR | 20 (40 μL) | 200 μL |
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| CENPLBA-20-GOGR | 20 (40 μL) | 200 μL |
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| CENPLBA-20-GORE | 20 (40 μL) | 200 μL |
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| CENPLBA-20-GRGO | 20 (40 μL) | 200 μL |
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| CENPLBA-20-GRRE | 20 (40 μL) | 200 μL |
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| CENPLBA-20-ORGR | 20 (40 μL) | 200 μL |
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| CENPLBA-20-REGO | 20 (40 μL) | 200 μL |
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| CENPLBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene is a member of the intracellular phospholipase A1 gene family. The protein encoded by this gene preferentially hydrolyzes phosphatidic acid. It is a cytosolic protein with some mitochondrial localization, and is thought to be involved in the regulation of mitochondrial dynamics. Overexpression of this gene causes fragmentation of the tubular structures in mitochondria, while depletion of the gene results in mitochondrial tubule elongation. Deletion of this gene in male mice caused fertility defects, resulting from disruption in the organization of the mitochondria during spermiogenesis. In humans, mutations in this gene have been associated with hereditary spastic paraplegia (HSP), also known as Strumpell-Lorrain disease, or, familial spastic paraparesis (FSP). This inherited disorder is characterized by progressive weakness and spasticity of the legs. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
Gene Details
Gene Symbol: DDHD1
Gene Name: DDHD Domain Containing 1
Chromosome: CHR14: 53503457-53620046
Locus: 14q22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CENPL FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DDHD1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping