CENP-M FISH Probe
The CENP-M FISH probe is designed to hybridize to the CENP-M gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CENPM-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CENPM-20-RE | 20 (40 μL) | 200 μL |  |
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| CENPM-20-GO | 20 (40 μL) | 200 μL |  |
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| CENPM-20-GR | 20 (40 μL) | 200 μL |  |
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| CENPM-20-AQ | 20 (40 μL) | 200 μL |  |
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| CENPM-20-DIG | 20 (40 μL) | 200 μL |  |
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| CENPM-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is an inner protein of the kinetochore, the multi-protein complex that binds spindle microtubules to regulate chromosome segregation during cell division. It belongs to the constitutive centromere-associated network protein group, whose members interact with outer kinetochore proteins and help to maintain centromere identity at each cell division cycle. The protein is structurally related to GTPases but cannot bind guanosine triphosphate. A point mutation that affects interaction with another constitutive centromere-associated network protein, CENP-I, impairs kinetochore assembly and chromosome alignment, suggesting that it is required for kinetochore formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Gene Details
Gene Symbol: CENPM
Gene Name: Centromere Protein M
Chromosome: CHR22: 42334740-42343148
Locus: 22q13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CENP-M FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CENPM-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping