CENP-B FISH Probe
The CENP-B FISH probe is designed to hybridize to the CENP-B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CENPB-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CENPB-20-RE | 20 (40 μL) | 200 μL |  |
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| CENPB-20-GO | 20 (40 μL) | 200 μL |  |
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| CENPB-20-GR | 20 (40 μL) | 200 μL |  |
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| CENPB-20-AQ | 20 (40 μL) | 200 μL |  |
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| CENPB-20-DIG | 20 (40 μL) | 200 μL |  |
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| CENPB-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CENPB
Gene Name: Centromere Protein B
Chromosome: CHR20: 3764497-3767337
Locus: 20p13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CENP-B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CENPB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping