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CDKN2C Break Apart FISH Probe

Empire Genomics’ CDKN2C Break Apart FISH Probe is designed to flank the CDKN2C gene and is typically used for detecting CDKN2C rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping
Download Datasheet Download FISH Protocol Download Material Safety Data Sheet

SKU Test Kits Buffer Dye Color Order Now
CDKN2CBA-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
CDKN2CBA-20-AQOR 20 (40 μL) 200 μL
CDKN2CBA-20-GOGR 20 (40 μL) 200 μL
CDKN2CBA-20-GORE 20 (40 μL) 200 μL
CDKN2CBA-20-GRGO 20 (40 μL) 200 μL
CDKN2CBA-20-GROR 20 (40 μL) 200 μL
CDKN2CBA-20-GRRE 20 (40 μL) 200 μL
CDKN2CBA-20-REGO 20 (40 μL) 200 μL
CDKN2CBA-20-REGR 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: CDKN2C

Gene Name: Cyclin Dependent Kinase Inhibitor 2C

Chromosome: CHR1: 51434366-51440306

Locus: 1p32.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Chromosomal aberrations in chordoid meningioma—An analysis

Chordoid meningiomas are a rare tumors that have been found to have deletions such as 22q, 18p, 14q, and 1p. Although the deletions are known, their correlation to their clinical findings is not as well known FISH analysis was used with a variety of our probes to see which deletion(s) each case under study had. It was found that any recurrence of chordoid meningioma had all four chromosome loci deleted.
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Product Details

Product: CDKN2C FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: CDKN2C-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping